Hello Giuseppe,
Welcome to LL.
Are you trying to make clones of systems that can be easily installed on to new hard drives if the old ones fail?
Or, are you just wanting to know if it is possible to install on a USB key?
Answer is "yes" you can make clones to a USB if it is large enough for that. Here are two programs that you can use for that:
Redo Backup & Recovery and
Clonezilla. Redo is available in the repositories, so you can use Synaptic to install it to your live LL installation CD/USB. Clonezilla must be downloaded and made into a bootable CD/USB. Either way, you need to operate them from a live CD/USB because you can not be using the drive that you are trying to clone.
And ...
"Yes" you can do a regular installation to a USB key just like you would to an internal hard drive. Your best bet is to make partitions on the USB ahead of time with GParted. Then boot computer with live installation CD/USB, plug in the USB you want to install to, then run the installer. When you get to "Installation Type" screen, choose "Something else". Next, select each partition you made on the USB, click "Change", set Mount Point and File System type for each, leave size as you made it in GParted. If USB is not very large, make Swap partition only 1-2GB. Then, most important -- set "device for boot loader installation" needs to be changed to the USB key. Just pick the device without any partition number. For example,
/dev/sdb -- not /dev/sd
b1.
Quote:Is the Linux Lite installation hardware dependent in some way ? Lets us explain better: we don't know if drivers are dinamically loaded at boot or they are "fixed" during the installation.
As long as you do not install any proprietary drivers for graphics or wireless cards, then it will adjust itself for whatever computer you boot into. As long as the computers you use it on can run from one of the default graphics drivers you should be fine using it on them.